Hello,
Are you getting the following message from a mail server or mail filtering appliance?
452 4.3.1 Insufficient system resources
There are several things to check including:
- Is the mail system receiving more connections than normal?
- Is some other trouble with the system causing it to run our of memory or connections?
- Is the system being attacked/abused?
- Has a misconfiguration caused a problem
- Check your logs
If everything looks OK and you are simply receiving more traffic than normal, for example growth over time, a temporary fix could be to configure more reputation and/or RBL blacklist filtering in front of the mail system experiencing the resource issues.