Hello,
I'll defer the final answer on this one to the Windows experts.
My best answer would be a Linux based mail server solution involving some automated scripts and a MySQL database. Do you have access to a Linux server for this project?
Here is an
old support guide from Microsoft that might be able to point you in the right direction for a free Windows based solution using the software that you already own.
I found
this site while doing some google searches. It does not appear to be a free solution. I contacted their support and they requested that you describe your project in more detail to them before making a purchase to make sure their software will meet your goals -
Sync2DB.com - Questionnaire
It looks like
this blog post and
this forum post might be useful to you too.
Please share the best solution with us so that people who have the same question in the future can benefit from the best answer.
and
to Email Questions!